Whole Blood is rarely given to patients because it is
wasteful and sometimes harmful to give blood components that are not
needed. Whole blood transfusions are necessary when very large amounts of
blood have been lost, otherwise blood components are given.
Red Blood Cells carry oxygen and are needed by surgical
patients or those with anemia or kidney disease
Platelet Rich Plasma is an intermediate stage in the
production of platelet concentrate and plasma components.
Frozen Red Blood Cells have been frozen to extend their
storage period. Very rare blood types are frozen to insure they are always
on hand.
Washed Red Blood Cells have been washed to prevent
reactions in some sensitive patients.
Filtered Red Blood Cells have been filtered to prevent
reactions in some sensitive patients.
Plasma is the yellow liquid portion of blood. It is also a
source of proteins that stop bleeding by forming blood clots.
Platelet Concentrates are fragile blood cells needed by
leukemia and other cancer patients to control bleeding.
Frozen Plasma to be manufactured into derivatives is
stored and shipped in the frozen state.
Fresh Frozen Plasma must be processed and frozen within
eight hours of the whole blood donation to preserve the less stable
clotting proteins. It is used mainly for people with bleeding
complications.
Cryoprecipitate, a part of the plasma, contains two
important clotting factors found in whole blood. It is used to treat two
common clotting disorders.
Fractionation is the process of breaking plasma down into
"fractions." When plasma gets mixed with certain chemicals,
proteins can be separated and processed into products which are stable and
easily stored. Some of the more common fractions are as follows:
Albumin - used in the treatment of certain kidney and
liver diseases. Because of the relative simplicity of storage and
administration, it is also used for emergency cases, such as accident or
shock victims, particularly where facilities for administering blood are
not available or where time does not permit its use.
Plasma Protein Fraction - similar to albumin; the two
products are often used interchangeably.
Gamma Globulin - contains the antibodies in plasma and is
able to modify or prevent measles and other infectious diseases, such as
some varieties of hepatitis.
HBIg, RHIg, VZIg - are gamma globulin products prepared
from the plasma of donors with high levels of specific desirable
antibodies.
Lyophilized Factor VIII - concentrates are used for the
treatment of Hemophilia A.
Other Clotting Factor Derivatives - contain concentrated
amounts of specific clotting factors and are used in certain less common
clotting disorders.